BDBM50183091 4-((bis(cyclohexylmethyl)amino)methyl)-N-(naphthalen-1-yl)thiazol-2-amine::CHEMBL207642

SMILES C(C1CCCCC1)N(CC1CCCCC1)Cc1csc(Nc2cccc3ccccc23)n1

InChI Key InChIKey=UWOWEDOVRFXUHU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50183091   

TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50183091(4-((bis(cyclohexylmethyl)amino)methyl)-N-(naphthal...)
Affinity DataIC50:  18nMAssay Description:Displacement of [125I]TARC from CCR4 expressed in human CEM cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50183091(4-((bis(cyclohexylmethyl)amino)methyl)-N-(naphthal...)
Affinity DataIC50:  530nMAssay Description:Inhibition of TARC-mediated CEM cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50183091(4-((bis(cyclohexylmethyl)amino)methyl)-N-(naphthal...)
Affinity DataIC50:  31nMAssay Description:Displacement of [125I]MDC from CCR4 expressed in human CEM cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed