BDBM50184796 1-((5-methyl-1-phenyl-1H-pyrazol-4-yl)methyl)-4-phenylpiperazine::CHEMBL377200

SMILES Cc1c(CN2CCN(CC2)c2ccccc2)cnn1-c1ccccc1

InChI Key InChIKey=VFZKZZYPGOBKJY-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184796   

TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184796(1-((5-methyl-1-phenyl-1H-pyrazol-4-yl)methyl)-4-ph...)
Affinity DataIC50:  78nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184796(1-((5-methyl-1-phenyl-1H-pyrazol-4-yl)methyl)-4-ph...)
Affinity DataIC50:  96nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed