BDBM50184979 CHEMBL3822689

SMILES CN1CCN(CC1)\C=C1/CCn2c1nc(=O)c1c(Cl)cccc21

InChI Key InChIKey=VLPRXFLUVHYBBT-VAWYXSNFSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50184979   

TargetProtein polybromo-1(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50184979(CHEMBL3822689)
Affinity DataKd:  124nMAssay Description:Binding affinity to His6-tagged human recombinant PB1 bromodomain isoform 5 expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by VP-ITC microca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50184979(CHEMBL3822689)
Affinity DataKd:  262nMAssay Description:Binding affinity to His6-tagged human recombinant SMARCA2B bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by VP-ITC microcalorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription activator BRG1(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50184979(CHEMBL3822689)
Affinity DataKd:  417nMAssay Description:Binding affinity to His6-tagged human recombinant SMARCA4 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by VP-ITC microcalorime...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed