BDBM50185005 CHEMBL3823483

SMILES Nc1ncc2cc3cnccc3c(N)c2n1

InChI Key InChIKey=PQAQQDCVZZTPPJ-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50185005   

TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
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Curated by ChEMBL

LigandBDBM50185005(CHEMBL3823483)Copy SMILESCopy InChI

Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of GST-tagged human recombinant CDK5/p25 expressed in Escherichia coli using histone H1 as substrate incubated for 30 mins in presence of ...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
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TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
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Curated by ChEMBL

LigandBDBM50185005(CHEMBL3823483)Copy SMILESCopy InChI

Affinity DataIC50:  28nMAssay Description:Inhibition of GST-tagged rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50185005(CHEMBL3823483)Copy SMILESCopy InChI

Affinity DataIC50:  41nMAssay Description:Inhibition of GST-tagged human recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI