BDBM50186381 3-(4-(5-(3-cyano-4-isopropoxyphenyl)-4H-1,2,4-triazol-3-yl)-3-methylphenyl)propanoic acid::CHEMBL379589

SMILES CC(C)Oc1ccc(cc1C#N)-c1nnc([nH]1)-c1ccc(CCC(O)=O)cc1C

InChI Key InChIKey=NHBYPAOUTOGPSB-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50186381   

TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50186381(3-(4-(5-(3-cyano-4-isopropoxyphenyl)-4H-1,2,4-tria...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at S1P3 receptor assessed as induction of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50186381(3-(4-(5-(3-cyano-4-isopropoxyphenyl)-4H-1,2,4-tria...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at S1P5 receptor assessed as induction of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50186381(3-(4-(5-(3-cyano-4-isopropoxyphenyl)-4H-1,2,4-tria...)
Affinity DataEC50:  380nMAssay Description:Agonist activity at S1P1 receptor assessed as induction of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed