BDBM50186405 3-(4-(5-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid::CHEMBL206940

SMILES CC(C)Oc1ccc(cc1Cl)-c1nc(no1)-c1ccc(CCC(O)=O)cc1C

InChI Key InChIKey=AOXVYFLXNZEUPI-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50186405   

TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50186405(3-(4-(5-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadia...)
Affinity DataEC50:  73nMAssay Description:Agonist activity at S1P5 receptor assessed as induction of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50186405(3-(4-(5-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadia...)
Affinity DataEC50:  940nMAssay Description:Agonist activity at S1P3 receptor assessed as induction of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50186405(3-(4-(5-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadia...)
Affinity DataEC50:  0.150nMAssay Description:Agonist activity at S1P1 receptor assessed as induction of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186405(3-(4-(5-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadia...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at S1P2 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50186405(3-(4-(5-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadia...)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at S1P3 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186405(3-(4-(5-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadia...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at S1P4 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50186405(3-(4-(5-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadia...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at S1P5 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50186405(3-(4-(5-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadia...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed