BDBM50186428 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)-N-(4-methoxyphenyl)acetamide::CHEMBL209776::US8618147, 7

SMILES COc1ccc(NC(=O)CC2CC(=NO2)c2ccc(O)cc2)cc1

InChI Key InChIKey=BAJJSZHHZTXAEW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186428   

TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50186428(2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)-N...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Mus musculus (Mouse))
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM50186428(2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)-N...)
Affinity DataIC50:  2.60E+4nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
In DepthDetails US Patent