BDBM50186519 CHEMBL214388::trans-3-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-1-amino-N-methyl-3-phenylcyclobutanecarboxamide

SMILES CNC(=O)[C@]1(N)C[C@](CO[C@H](C)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)(C1)c1ccccc1

InChI Key InChIKey=OHDQKQGDHONPAR-IFZYUDKTSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186519   

TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186519(CHEMBL214388 | trans-3-(((R)-1-(3,5-bis(trifluorom...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186519(CHEMBL214388 | trans-3-(((R)-1-(3,5-bis(trifluorom...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]neurokinin B from human recombinant NK3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed