BDBM50186522 CHEMBL379072::trans-N-{3-[(R)-1-(3,5-bis-trifluoromethyl-phenyl)-ethoxymethyl]-3-phenyl-cyclobutyl}-acetamide

SMILES C[C@@H](OC[C@]1(C[C@@H](C1)NC(C)=O)c1ccccc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=ZOPRZQRKBZNHLP-IFZYUDKTSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186522   

TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186522(CHEMBL379072 | trans-N-{3-[(R)-1-(3,5-bis-trifluor...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186522(CHEMBL379072 | trans-N-{3-[(R)-1-(3,5-bis-trifluor...)
Affinity DataKi:  631nMAssay Description:Displacement of [3H]neurokinin B from human recombinant NK3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed