BDBM50186585 2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-6-methyl-1H-indol-4-yloxy)acetic acid::CHEMBL208315

SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cc(C)cc2n1Cc1ccccc1

InChI Key InChIKey=POYSBCQIOOZMFS-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50186585   

TargetPhospholipase A2, membrane associated(Mus musculus)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50186585(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-6-meth...)
Affinity DataIC50:  50nMAssay Description:Inhibition of mouse recombinant sPLA2 G2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup IIE secretory phospholipase A2(Mus musculus)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50186585(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-6-meth...)
Affinity DataIC50:  75nMAssay Description:Inhibition of mouse recombinant sPLA2 G2EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2 group V(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50186585(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-6-meth...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human recombinant sPLA2 G5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2 group V(Mus musculus)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50186585(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-6-meth...)
Affinity DataIC50:  750nMAssay Description:Inhibition of mouse recombinant sPLA2 G5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup 10 secretory phospholipase A2(Mus musculus)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50186585(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-6-meth...)
Affinity DataIC50:  75nMAssay Description:Inhibition of mouse recombinant sPLA2 G10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50186585(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-6-meth...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant sPLA2 G1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50186585(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-6-meth...)
Affinity DataIC50:  125nMAssay Description:Inhibition of human recombinant sPLA2 G2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup IIE secretory phospholipase A2(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50186585(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-6-meth...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant sPLA2 G2EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Mus musculus)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50186585(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-6-meth...)
Affinity DataIC50:  200nMAssay Description:Inhibition of mouse recombinant sPLA2 G1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup 10 secretory phospholipase A2(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50186585(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-6-meth...)
Affinity DataIC50:  75nMAssay Description:Inhibition of human recombinant sPLA2 G10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed