BDBM50186816 3-[4-(3'-cyano-biphenyl-4-yl)-1-cyclopentyl-piperidin-4-yl]-N-(3,5-dichloro-phenyl)-propionamide::CHEMBL210343

SMILES Clc1cc(Cl)cc(NC(=O)CCC2(CCN(CC2)C2CCCC2)c2ccc(cc2)-c2cccc(c2)C#N)c1

InChI Key InChIKey=FKTRDONUASUZHX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186816   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186816(3-[4-(3'-cyano-biphenyl-4-yl)-1-cyclopentyl-piperi...)
Affinity DataKi:  42nMAssay Description:Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186816(3-[4-(3'-cyano-biphenyl-4-yl)-1-cyclopentyl-piperi...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity at human MCHR2 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed