BDBM50186927 5-(4-cyclohexylphenyl)-3-o-tolyl-1,2,4-oxadiazole::CHEMBL208786

SMILES Cc1ccccc1-c1noc(n1)-c1ccc(cc1)C1CCCCC1

InChI Key InChIKey=UTDMZFXOTRMGDB-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50186927   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186927(5-(4-cyclohexylphenyl)-3-o-tolyl-1,2,4-oxadiazole ...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186927(5-(4-cyclohexylphenyl)-3-o-tolyl-1,2,4-oxadiazole ...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at S1P4 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186927(5-(4-cyclohexylphenyl)-3-o-tolyl-1,2,4-oxadiazole ...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at S1P3 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186927(5-(4-cyclohexylphenyl)-3-o-tolyl-1,2,4-oxadiazole ...)
Affinity DataEC50:  266nMAssay Description:Agonist activity at S1P5 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186927(5-(4-cyclohexylphenyl)-3-o-tolyl-1,2,4-oxadiazole ...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at S1P2 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed