BDBM50187048 (S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-phenyl-2-(2-(piperidin-1-yl)ethylamino)acetamide::CHEMBL209267

SMILES FC(F)(F)c1cc(CNC(=O)[C@@H](NCCN2CCCCC2)c2ccccc2)cc(c1)C(F)(F)F

InChI Key InChIKey=BHCROBUDGYXOFC-NRFANRHFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187048   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187048((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-phenyl-2-...)
Affinity DataIC50:  219nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187048((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-phenyl-2-...)
Affinity DataIC50:  219nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187048((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-phenyl-2-...)
Affinity DataIC50:  220nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed