BDBM50187817 5-(2-chloro-4-iodophenylamino)-3-hydroxy-N-isopropylisothiazole-4-carboxamidine::5-2-chloro-4-iodophenylamino)-3-hydroxy-N-isopropylisothiazole-4-carboximidamide::CHEMBL213992

SMILES CC(C)NC(=N)c1c(Nc2ccc(I)cc2Cl)s[nH]c1=O

InChI Key InChIKey=FQOBLOHRHRCTMT-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187817   

TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50187817(5-(2-chloro-4-iodophenylamino)-3-hydroxy-N-isoprop...)
Affinity DataIC50:  42nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50187817(5-(2-chloro-4-iodophenylamino)-3-hydroxy-N-isoprop...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50187817(5-(2-chloro-4-iodophenylamino)-3-hydroxy-N-isoprop...)
Affinity DataIC50:  42nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed