BDBM50187848 5-(2,3-dichlorophenylamino)-3-hydroxy-N-(1-hydroxypropan-2-yl)isothiazole-4-carboxamidine::5-2,3-dichlorophenylamino)-3-hydroxy-N-1-hydroxypropan-2-yl)isothiazole-4-carboximidamide::CHEMBL375609
SMILES CC(CO)NC(=N)c1c(Nc2cccc(Cl)c2Cl)s[nH]c1=O
InChI Key InChIKey=MTLKDHYIODZMOW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50187848
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Affinity DataEC50: 375nMAssay Description:Inhibitory activity against MEK-1More data for this Ligand-Target Pair