BDBM50188083 5-(1-(3,4,5-trimethoxyphenyl)ethyl)pyrimidine-2,4-diamine::5-[1-(3,4,5-Trimethoxy-phenyl)-ethyl]-pyrimidine-2,4-diamine::CHEMBL141781

SMILES COc1cc(cc(OC)c1OC)C(C)c1cnc(N)nc1N

InChI Key InChIKey=XTYBLHRJSJHVJV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188083   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Dartmouth College

Curated by ChEMBL
LigandPNGBDBM50188083(5-(1-(3,4,5-trimethoxyphenyl)ethyl)pyrimidine-2,4-...)
Affinity DataIC50:  3.40E+5nMAssay Description:Inhibition of Cryptosporidium hominis DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University Of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50188083(5-(1-(3,4,5-trimethoxyphenyl)ethyl)pyrimidine-2,4-...)
Affinity DataIC50:  1.00E+5nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University Of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50188083(5-(1-(3,4,5-trimethoxyphenyl)ethyl)pyrimidine-2,4-...)
Affinity DataIC50:  1.00E+5nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed