BDBM50188429 CHEMBL376654::[D-Dab(CO-NH-OCH3)3, 4Aph(CO-NH-OCH3)5,D-4Aph(CO-NHOCH3)6]-degarelix

SMILES CONC(=O)NCC[C@@H](NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(NC(=O)NOC)cc1)C(=O)N[C@H](Cc1ccc(NC(=O)NOC)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(N)=O

InChI Key InChIKey=HXFYTUYPTGPWGX-BYVNKILGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188429   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50188429(CHEMBL376654 | [D-Dab(CO-NH-OCH3)3, 4Aph(CO-NH-OCH...)
Affinity DataIC50:  1.49nMAssay Description:Antagonist activity at human GnRH receptor expressed in HEK293 cells as inhibition of GnRH-induced LH secretion by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed