BDBM50188476 CHEMBL209876::N-4-[4-(3-chloro-2-methoxyphenyl)piperazin-1-yl]butyl][2.2]-paracyclophane-4-carboxamide

SMILES COc1c(Cl)cccc1N1CCN(CCCCNC(=O)c2cc3CCc4ccc(CCc2cc3)cc4)CC1

InChI Key InChIKey=OWMILJDHSTVDQS-UHFFFAOYSA-N

Data  6 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50188476   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188476(CHEMBL209876 | N-4-[4-(3-chloro-2-methoxyphenyl)pi...)
Affinity DataKi:  0.460nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188476(CHEMBL209876 | N-4-[4-(3-chloro-2-methoxyphenyl)pi...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor of porcine cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188476(CHEMBL209876 | N-4-[4-(3-chloro-2-methoxyphenyl)pi...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]spiperone from human D2 short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188476(CHEMBL209876 | N-4-[4-(3-chloro-2-methoxyphenyl)pi...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188476(CHEMBL209876 | N-4-[4-(3-chloro-2-methoxyphenyl)pi...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]spiperone from human D2 long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188476(CHEMBL209876 | N-4-[4-(3-chloro-2-methoxyphenyl)pi...)
Affinity DataKi:  970nMAssay Description:Displacement of [3H]SCH 23390 from D1 receptor of porcine striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188476(CHEMBL209876 | N-4-[4-(3-chloro-2-methoxyphenyl)pi...)
Affinity DataEC50:  18nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells assessed as rate of [3H]thymidine incorporation by mitogenesis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed