BDBM50188870 4-phenyl-8-(4-phenyl-tetrahydro-pyran-4-yl)-2,8-diaza-spiro[4.5]decan-1-one::CHEMBL211633::CHEMBL559007

SMILES O=C1NCC(c2ccccc2)C11CCN(CC1)C1(CCOCC1)c1ccccc1

InChI Key InChIKey=UQZKADKVZVDMTP-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188870   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188870(4-phenyl-8-(4-phenyl-tetrahydro-pyran-4-yl)-2,8-di...)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188870(4-phenyl-8-(4-phenyl-tetrahydro-pyran-4-yl)-2,8-di...)
Affinity DataIC50: >1.40E+4nMAssay Description:Inhibition of hERG potassium channel expressed in CHO cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188870(4-phenyl-8-(4-phenyl-tetrahydro-pyran-4-yl)-2,8-di...)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed