BDBM50189308 CHEMBL269032

SMILES NC(=N)c1ccc(cc1)N1CCCN(CC1)c1ccc(cc1)C(N)=N

InChI Key InChIKey=INGAEVQROKUCFW-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50189308   

TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189308(CHEMBL269032)
Affinity DataKi:  397nMAssay Description:Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189308(CHEMBL269032)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 6(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189308(CHEMBL269032)
Affinity DataKi:  4.39E+3nMAssay Description:Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189308(CHEMBL269032)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of human thrombin using Cbz-Gly-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Bos taurus)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189308(CHEMBL269032)
Affinity DataKi:  7.83E+3nMAssay Description:Inhibition of bovine factor 10a using Boc-Ile-Glu-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed