BDBM50189370 CHEMBL212870::N'-(2-(((3S)-2-hydroxy-5-oxo-tetrahydrofuran-3-yl)carbamoyl)-2,3-dihydro-1H-indene-2-carbonyl)-1-naphthohydrazide

SMILES OC1OC(=O)C[C@@H]1NC(=O)C1(Cc2ccccc2C1)C(=O)NNC(=O)c1cccc2ccccc12

InChI Key InChIKey=RYTHJGWSBNDVTE-AJZOCDQUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189370   

TargetCaspase-3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189370(CHEMBL212870 | N'-(2-(((3S)-2-hydroxy-5-oxo-tetrah...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189370(CHEMBL212870 | N'-(2-(((3S)-2-hydroxy-5-oxo-tetrah...)
Affinity DataIC50:  420nMAssay Description:Inhibition of caspase8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189370(CHEMBL212870 | N'-(2-(((3S)-2-hydroxy-5-oxo-tetrah...)
Affinity DataIC50:  40nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed