BDBM50189500 CHEMBL3827664
SMILES Cn1cc(cn1)-c1ccc(cc1)-c1cnc(N)c2ccc(cc12)C(=O)NC1CC1
InChI Key InChIKey=HAEDHIQEQOEOHP-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50189500
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Binding affinity to CDK8 (unknown origin) expressed in human 7dF3 cells preincubated for 2 hrs followed by beta-oestradiol addition measured after 24...More data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Competitive binding affinity to full length His-tagged human recombinant CDK8/cyclin C expressed in baculovirus after 20 mins in presence of Alexa647...More data for this Ligand-Target Pair