BDBM50189750 5-[5-(2-hydroxyphenyl)furan-2-ylmethylene]thiazolidine-2, 4-dione::CHEMBL208652

SMILES OC1=NC(=O)C(S1)=Cc1ccc(o1)-c1ccccc1O

InChI Key InChIKey=OCDGTZUIGBFFHU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50189750   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50189750(5-[5-(2-hydroxyphenyl)furan-2-ylmethylene]thiazoli...)
Affinity DataIC50:  30nMAssay Description:Inhibition of PI3Kgamma (unknown origin) assessed as decrease in fluorescence intensity using phosphorylated substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189750(5-[5-(2-hydroxyphenyl)furan-2-ylmethylene]thiazoli...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50189750(5-[5-(2-hydroxyphenyl)furan-2-ylmethylene]thiazoli...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189750(5-[5-(2-hydroxyphenyl)furan-2-ylmethylene]thiazoli...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189750(5-[5-(2-hydroxyphenyl)furan-2-ylmethylene]thiazoli...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed