BDBM50190457 CHEMBL211072::N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[4-(3,4-dihydroxyphenyl)butyl]-guanidine

SMILES NC(NC(=O)c1nc(Cl)c(N)nc1N)=NCCCCc1ccc(O)c(O)c1

InChI Key InChIKey=CHSLRCSFKFQMCE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190457   

TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190457(CHEMBL211072 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  42nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed