BDBM50190602 CHEMBL209809::cis-(3R,6R)-(6-benzhydryl-tetrahydropyran-3-yl)-(4-hydroxy-benzyl)-amine

SMILES Oc1ccc(CN[C@@H]2CC[C@@H](OC2)C(c2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=CFCFEXCFOQWYQK-ISKFKSNPSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50190602   

TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190602(CHEMBL209809 | cis-(3R,6R)-(6-benzhydryl-tetrahydr...)
Affinity DataKi:  41nMAssay Description:Inhibition of NET-mediated [3H]NE uptake in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190602(CHEMBL209809 | cis-(3R,6R)-(6-benzhydryl-tetrahydr...)
Affinity DataKi:  67nMAssay Description:Inhibition of DAT-mediated [3H]DA uptake in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190602(CHEMBL209809 | cis-(3R,6R)-(6-benzhydryl-tetrahydr...)
Affinity DataKi:  114nMAssay Description:Inhibition of [3H]WIN 35428 binding to rat striatum DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190602(CHEMBL209809 | cis-(3R,6R)-(6-benzhydryl-tetrahydr...)
Affinity DataKi:  187nMAssay Description:Inhibition of SERT-mediated [3H]5HT uptake in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed