BDBM50190605 CHEMBL209603::cis-(3S-6S)-(6-benzhydryl-tetrahydropyran-3-yl)-(1H-indol-5-ylmethyl)amine

SMILES C(N[C@H]1CC[C@H](OC1)C(c1ccccc1)c1ccccc1)c1ccc2[nH]ccc2c1

InChI Key InChIKey=UJBRKEMHKNOCKI-AHWVRZQESA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50190605   

TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190605(CHEMBL209603 | cis-(3S-6S)-(6-benzhydryl-tetrahydr...)
Affinity DataKi:  6.60nMAssay Description:Inhibition of NET-mediated [3H]NE uptake in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190605(CHEMBL209603 | cis-(3S-6S)-(6-benzhydryl-tetrahydr...)
Affinity DataKi:  15nMAssay Description:Inhibition of SERT-mediated [3H]5HT uptake in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190605(CHEMBL209603 | cis-(3S-6S)-(6-benzhydryl-tetrahydr...)
Affinity DataKi:  214nMAssay Description:Inhibition of DAT-mediated [3H]DA uptake in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190605(CHEMBL209603 | cis-(3S-6S)-(6-benzhydryl-tetrahydr...)
Affinity DataKi:  338nMAssay Description:Inhibition of [3H]WIN 35428 binding to rat striatum DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed