BDBM50190606 (2S,4R,5R)-2-benzhydryl-5-(4-hydroxy-benzylamino)-tetrahydropyran-4-ol::CHEMBL211994

SMILES O[C@@H]1C[C@H](OC[C@H]1NCc1ccc(O)cc1)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=ORUGDEVHISMQAF-SMIHKQSGSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50190606   

TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190606((2S,4R,5R)-2-benzhydryl-5-(4-hydroxy-benzylamino)-...)
Affinity DataKi:  10nMAssay Description:Inhibition of NET-mediated [3H]NE uptake in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190606((2S,4R,5R)-2-benzhydryl-5-(4-hydroxy-benzylamino)-...)
Affinity DataKi:  172nMAssay Description:Inhibition of DAT-mediated [3H]DA uptake in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190606((2S,4R,5R)-2-benzhydryl-5-(4-hydroxy-benzylamino)-...)
Affinity DataKi:  234nMAssay Description:Inhibition of [3H]WIN 35428 binding to rat striatum DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190606((2S,4R,5R)-2-benzhydryl-5-(4-hydroxy-benzylamino)-...)
Affinity DataKi:  237nMAssay Description:Inhibition of SERT-mediated [3H]5HT uptake in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed