BDBM50191535 2-[4-(biphenyl-2-ylmethoxy)-2-trifluoromethylphenyl]-1-cyclohexyl-1H-benzoimidazole-5-carboxylic acid::CHEMBL384679
SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(OCc2ccccc2-c2ccccc2)cc1C(F)(F)F
InChI Key InChIKey=WKBJPSSQTDQRLU-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50191535
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 930nMAssay Description:Inhibition of HCV 1b BK six His-tagged C-terminal truncated 544 amino acid NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.07E+6nMAssay Description:Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 minMore data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+6nMAssay Description:Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 minMore data for this Ligand-Target Pair