BDBM50191704 (R)-2-methyl-N-(4-(trifluoromethyl)phenyl)-4-(3-(trifluoromethyl)pyridin-2-yl)piperazine-1-carboxamide::CHEMBL214607
SMILES C[C@@H]1CN(CCN1C(=O)Nc1ccc(cc1)C(F)(F)F)c1ncccc1C(F)(F)F
InChI Key InChIKey=SLZAAONIJRKRLZ-GFCCVEGCSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50191704
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Antagonist activity against capsaicin-activated human VR1 by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human TRPV1More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Antagonist activity against low pH(5.0-5.5)-activated rat VR1More data for this Ligand-Target Pair