BDBM50192123 2-(4-(ethyl(2-methoxy-1-phenylethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL215598

SMILES CCN(C(COC)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=RTQPHBRRDAKJST-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50192123   

TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192123(2-(4-(ethyl(2-methoxy-1-phenylethyl)amino)phenyl)-...)
Affinity DataEC50:  900nMAssay Description:Transactivation of LXRalpha by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192123(2-(4-(ethyl(2-methoxy-1-phenylethyl)amino)phenyl)-...)
Affinity DataIC50:  400nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192123(2-(4-(ethyl(2-methoxy-1-phenylethyl)amino)phenyl)-...)
Affinity DataEC50:  100nMAssay Description:Transactivation of LXRbeta by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192123(2-(4-(ethyl(2-methoxy-1-phenylethyl)amino)phenyl)-...)
Affinity DataIC50:  300nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed