BDBM50192414 4-(3-amino-2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL213313

SMILES Nc1cccc(c1Cl)-c1cc2[nH]c3ccc(O)cc3c2c2C(=O)NC(=O)c12

InChI Key InChIKey=VRMZXUBTUACHFT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50192414   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50192414(4-(3-amino-2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]...)
Affinity DataIC50:  480nMAssay Description:Inhibition at human Chk1 in presence of 4 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50192414(4-(3-amino-2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50192414(4-(3-amino-2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human Wee1 in presence of 9.5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed