BDBM50192437 4-(2,3-dichlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL384477

SMILES Oc1ccc2[nH]c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=NDHIKTIBSHPKAT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50192437   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50192437(4-(2,3-dichlorophenyl)-9-hydroxypyrrolo[3,4-c]carb...)
Affinity DataIC50:  240nMAssay Description:Inhibition at human Chk1 in presence of 4 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50192437(4-(2,3-dichlorophenyl)-9-hydroxypyrrolo[3,4-c]carb...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50192437(4-(2,3-dichlorophenyl)-9-hydroxypyrrolo[3,4-c]carb...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human Wee1 in presence of 9.5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed