BDBM50192474 CHEMBL215191::benzyl-(7,8-dimethoxy-10,11-dihydro-5H-2,4,5,11-tetraaza-dibenzo[a,d]cyclohepten-1-yl)-amine
SMILES COc1cc2CNc3c(NCc4ccccc4)ncnc3Nc2cc1OC
InChI Key InChIKey=SLYLBACSXAVTAA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50192474
Affinity DataIC50: 200nMAssay Description:Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Imclone Systems
Curated by ChEMBL
Imclone Systems
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of KDR measured as pGAT-biotin peptide phosphorylation by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of EGFR autophosphorylation in DiFi cells by ELISAMore data for this Ligand-Target Pair