BDBM50192836 CHEMBL3911672::US10188627, Compound 8m

SMILES CN(Cc1ccccc1OCc1ccc(CC(O)=O)cc1)C(=O)c1ccc(cc1)-c1ccco1

InChI Key InChIKey=RTCGQTKMNNJMFH-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50192836   

TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50192836(CHEMBL3911672 | US10188627, Compound 8m)
Affinity DataEC50:  13nMAssay Description:Transactivation of ProLink tagged human PPARdelta transfected in CHO-K1 cells assessed as interaction with EA labelled SRCP after 3 to 16 hrs by beta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50192836(CHEMBL3911672 | US10188627, Compound 8m)
Affinity DataEC50:  1.32E+3nMAssay Description:Transactivation of human Gal4-PPARdelta LBD transfected in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPPAR delta protein(Rattus norvegicus (Rat))
Mitobridge

US Patent
LigandPNGBDBM50192836(CHEMBL3911672 | US10188627, Compound 8m)
Affinity DataEC50:  13.5nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50192836(CHEMBL3911672 | US10188627, Compound 8m)
Affinity DataEC50:  1.32E+3nMAssay Description:Cell Handling: PathHunter NHR cell lines were expanded from freezer stocks according to standard procedures. Cells were seeded in a total volume of 2...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50192836(CHEMBL3911672 | US10188627, Compound 8m)
Affinity DataEC50:  13.5nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
In DepthDetails US Patent