BDBM50193179 CHEMBL218410::tert-butyl 1-(1-isopropylpiperazine-4-carbonyl)piperidine-4-carboxylate

SMILES CC(C)N1CCN(CC1)C(=O)N1CCC(CC1)C(=O)OC(C)(C)C

InChI Key InChIKey=GDAGKQMCMNZJDE-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50193179   

TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50193179(CHEMBL218410 | tert-butyl 1-(1-isopropylpiperazine...)
Affinity DataKi:  25nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50193179(CHEMBL218410 | tert-butyl 1-(1-isopropylpiperazine...)
Affinity DataKi:  25nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50193179(CHEMBL218410 | tert-butyl 1-(1-isopropylpiperazine...)
Affinity DataIC50:  1.01E+5nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50193179(CHEMBL218410 | tert-butyl 1-(1-isopropylpiperazine...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50193179(CHEMBL218410 | tert-butyl 1-(1-isopropylpiperazine...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50193179(CHEMBL218410 | tert-butyl 1-(1-isopropylpiperazine...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed