BDBM50193657 CHEMBL3955994

SMILES CC(C)Oc1ccc2CCN(Cc3c(C)cc(C)[nH]c3=O)C(=O)c2c1C

InChI Key InChIKey=LMEVDBXFNKOLNE-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193657   

TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50193657(CHEMBL3955994)
Affinity DataIC50:  160nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50193657(CHEMBL3955994)
Affinity DataKd:  37nMAssay Description:Binding affinity to EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed