BDBM50193684 CHEMBL384362::N-(2-(2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide

SMILES FC(F)(F)c1ccc(CCC(=O)Nc2ccc3nc(ccc3c2)N2CC3CC2CO3)cc1

InChI Key InChIKey=DCTXDZRQZOKNLS-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193684   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50193684(CHEMBL384362 | N-(2-(2-oxa-5-azabicyclo[2.2.1]hept...)
Affinity DataIC50:  13nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from human MCH-R1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50193684(CHEMBL384362 | N-(2-(2-oxa-5-azabicyclo[2.2.1]hept...)
Affinity DataEC50:  70nMAssay Description:Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing rat MCH-R1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed