BDBM50193921 3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-ylsulfonyl)acrylamide::CHEMBL220802

SMILES O=C(NS(=O)(=O)c1cccs1)\C=C\c1ccccc1Cc1ccc2ccccc2c1

InChI Key InChIKey=MOOPBYUCHZCDPA-BUHFOSPRSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50193921   

TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi:  263nMAssay Description:Inhibition of EP3 receptor in presence of 0.005 % HASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi:  280nMAssay Description:Binding affinity to EP3 receptor in presence of HSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi: >500nMAssay Description:Binding affinity to IP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi: >500nMAssay Description:Binding affinity to TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi: >500nMAssay Description:Binding affinity to DP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi: >500nMAssay Description:Binding affinity to FP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity to EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi:  8.60E+3nMAssay Description:Binding affinity to EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi:  9.60E+3nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed