BDBM50194067 5-4-3-fluoro-5-trifluoromethyl)phenoxy)phenylamino)-3-hydroxy-N-1-hydroxypropan-2-yl)isothiazole-4-carboximidamide::CHEMBL425980
SMILES CC(CO)N=C(N)c1c(Nc2ccc(Oc3cc(F)cc(c3)C(F)(F)F)cc2)s[nH]c1=O
InChI Key InChIKey=LONIKTNABVADEH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50194067
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair