BDBM50194654 (2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chlorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-(4-piperidinylmethyl)pyrrolidine-2-carboxamide::CHEMBL378872

SMILES O[C@@H]1C[C@H](N(C1)C(=O)CC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)N1CCC[C@@H]1C(=O)NCC1CCNCC1

InChI Key InChIKey=BHAUVKSALKMKRU-SLGZMBILSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50194654   

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194654((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chloroph...)
Affinity DataKi:  0.390nMAssay Description:Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194654((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chloroph...)
Affinity DataKi:  53nMAssay Description:Inhibition of [3H]NMS binding to human cloned M4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194654((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chloroph...)
Affinity DataKi:  93nMAssay Description:Inhibition of [3H]NMS binding to human cloned M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194654((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chloroph...)
Affinity DataKi:  310nMAssay Description:Inhibition of [3H]NMS binding to human cloned M2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50194654((2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chloroph...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of [3H]NMS binding to human cloned M5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed