BDBM50194735 CHEMBL215961::diphenyl 1-[(N-p-cyanobenzenesulfonyl-D-seryl)-L-alanyl]-amino-2-(4-guanidinophenyl)ethane-phosphonate

SMILES [#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-[#8])-[#7]S(=O)(=O)c1ccc(cc1)C#N)-[#6](=O)-[#7]-[#6](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])P(=O)([#8]-c1ccccc1)[#8]-c1ccccc1

InChI Key InChIKey=QDCFZMDANJYLAS-NJIWFKEJSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50194735   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194735(CHEMBL215961 | diphenyl 1-[(N-p-cyanobenzenesulfon...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194735(CHEMBL215961 | diphenyl 1-[(N-p-cyanobenzenesulfon...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194735(CHEMBL215961 | diphenyl 1-[(N-p-cyanobenzenesulfon...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194735(CHEMBL215961 | diphenyl 1-[(N-p-cyanobenzenesulfon...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of recombinant tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed