BDBM50194739 CHEMBL213216::diphenyl 1-[(N-2-thienyl-D-seryl)-L-alanyl]amino-2-(4-guanidinophenyl)ethanephosphonate

SMILES [#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-[#8])-[#7]-[#6](=O)-c1cccs1)-[#6](=O)-[#7]-[#6](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])P(=O)([#8]-c1ccccc1)[#8]-c1ccccc1

InChI Key InChIKey=MLDAHNABORMCIW-UMVYAPTFSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50194739   

TargetProthrombin(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194739(CHEMBL213216 | diphenyl 1-[(N-2-thienyl-D-seryl)-L...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194739(CHEMBL213216 | diphenyl 1-[(N-2-thienyl-D-seryl)-L...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194739(CHEMBL213216 | diphenyl 1-[(N-2-thienyl-D-seryl)-L...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of recombinant tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Bos taurus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194739(CHEMBL213216 | diphenyl 1-[(N-2-thienyl-D-seryl)-L...)
Affinity DataIC50:  2.50E+5nMAssay Description:Inhibition of bovine F10a at 250 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194739(CHEMBL213216 | diphenyl 1-[(N-2-thienyl-D-seryl)-L...)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed