BDBM50194744 CHEMBL385897::diphenyl 1-[(N-naphthalenesulfonyl-D-seryl)-L-alanyl]amino-2-(4-guanidinophenyl)ethanephosphonate

SMILES [#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-[#8])-[#7]S(=O)(=O)c1cccc2ccccc12)-[#6](=O)-[#7]-[#6](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])P(=O)([#8]-c1ccccc1)[#8]-c1ccccc1

InChI Key InChIKey=VXFFMDVLGNSKLD-TYTGLEOTSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50194744   

TargetTissue-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194744(CHEMBL385897 | diphenyl 1-[(N-naphthalenesulfonyl-...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of recombinant tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Bos taurus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194744(CHEMBL385897 | diphenyl 1-[(N-naphthalenesulfonyl-...)
Affinity DataIC50:  9.60E+4nMAssay Description:Inhibition of bovine F10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194744(CHEMBL385897 | diphenyl 1-[(N-naphthalenesulfonyl-...)
Affinity DataIC50:  990nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194744(CHEMBL385897 | diphenyl 1-[(N-naphthalenesulfonyl-...)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194744(CHEMBL385897 | diphenyl 1-[(N-naphthalenesulfonyl-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed