BDBM50195187 6-chloro-5-(2-fluorophenylamino)-1H-indazole-4,7-dione::CHEMBL220006

SMILES Fc1ccccc1NC1=C(Cl)C(=O)c2[nH]ncc2C1=O

InChI Key InChIKey=SFTFPPBMKWFSMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195187   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50195187(6-chloro-5-(2-fluorophenylamino)-1H-indazole-4,7-d...)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of AktMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50195187(6-chloro-5-(2-fluorophenylamino)-1H-indazole-4,7-d...)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of Akt1 activity assessed as decrease in GSK3 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed