BDBM50195498 CHEMBL426208::methyl 2-((1s,4s)-4-(4-amino-3,5-dichloro-N-cyclopropylbenzamido)-N-methylcyclohexanecarboxamido)acetate

SMILES COC(=O)CN(C)C(=O)[C@@H]1CC[C@@H](CC1)N(C1CC1)C(=O)c1cc(Cl)c(N)c(Cl)c1

InChI Key InChIKey=DAEAJVPMQNJONR-XBXGTLAGSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50195498   

Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195498(CHEMBL426208 | methyl 2-((1s,4s)-4-(4-amino-3,5-di...)
Affinity DataKi:  14nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195498(CHEMBL426208 | methyl 2-((1s,4s)-4-(4-amino-3,5-di...)
Affinity DataKi:  60nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195498(CHEMBL426208 | methyl 2-((1s,4s)-4-(4-amino-3,5-di...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195498(CHEMBL426208 | methyl 2-((1s,4s)-4-(4-amino-3,5-di...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195498(CHEMBL426208 | methyl 2-((1s,4s)-4-(4-amino-3,5-di...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed