BDBM50196392 3-hydroxy-N-(2-hydroxy-1-methyl-ethyl)-5-(4-phenylamino-phenylamino)-isothiazole-4-carboxamidine::3-hydroxy-N-1-hydroxypropan-2-yl)-5-4-phenylamino)phenylamino)isothiazole-4-carboximidamide::CHEMBL253116
SMILES CC(CO)N=C(N)c1c(Nc2ccc(Nc3ccccc3)cc2)s[nH]c1=O
InChI Key InChIKey=WHWRHSZXRYNDDO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50196392
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Affinity DataEC50: 45nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibition of Chk2 kinaseMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1/beta-2(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of p70 S6 kinaseMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
TargetAurora kinase A(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL
Valeant Pharmaceuticals Research & Development
Curated by ChEMBL