BDBM50196628 CHEMBL3932095::US10167270, Compound 9d
SMILES C1CC(Nc2nc(nc3ccccc23)-c2cccnc2)c2ccccc2C1
InChI Key InChIKey=XGFDEYBZTPSJCH-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50196628
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 872nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 872nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair