BDBM50196675 CHEMBL3900593

SMILES CCOc1ccc(CC2CC(C2)C(=O)NO)cc1-c1nc2c(CC)nn(C)c2c(=O)[nH]1

InChI Key InChIKey=WFSWUBOROARLDR-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50196675   

TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196675(CHEMBL3900593)
Affinity DataIC50:  91nMAssay Description:Inhibition of full length recombinant human N-terminal GST tagged HDAC6 expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196675(CHEMBL3900593)
Affinity DataIC50:  490nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged HDAC2 expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196675(CHEMBL3900593)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of recombinant N-terminal GST tagged PDE6C (unknown origin) expressed in baculovirus infected Sf9 cells using cGMP as substrate by malachi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196675(CHEMBL3900593)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant PDE3A (unknown origin) expressed in baculovirus infected Sf9 cells using cAMP as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196675(CHEMBL3900593)
Affinity DataIC50:  60nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196675(CHEMBL3900593)
Affinity DataIC50:  310nMAssay Description:Inhibition of full length recombinant human C-terminal His/Flag-tagged HDAC1 expressed in baculovirus infected Sf9 cells using fluorogenic HDAC subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196675(CHEMBL3900593)
Affinity DataIC50:  322nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed