BDBM50197049 CHEMBL458273

SMILES N[C@@H]([C@H](Cc1ccccc1)C(O)=O)C(O)=O

InChI Key InChIKey=KMVYGTIPJNGNRD-IUCAKERBSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50197049   

TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50197049(CHEMBL458273)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50197049(CHEMBL458273)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50197049(CHEMBL458273)
Affinity DataIC50:  5.13E+4nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50197049(CHEMBL458273)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50197049(CHEMBL458273)
Affinity DataIC50:  800nMAssay Description:Inhibition of human EAAT3 transfected in mouse C17.2 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 5 mins by liquid scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50197049(CHEMBL458273)
Affinity DataIC50:  4.27E+4nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50197049(CHEMBL458273)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of human EAAT1 transfected in mouse C17.2 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 5 mins by liquid scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50197049(CHEMBL458273)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human EAAT2 transfected in mouse C17.2 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 5 mins by liquid scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50197049(CHEMBL458273)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed