BDBM50197709 CHEMBL3984621
SMILES Nc1c(cnn1-c1cc(O)ccc1Cl)C(=O)c1cc2cc(CN3CCOCC3)ccc2[nH]1
InChI Key InChIKey=IWBVZILESKBVJL-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50197709
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human KDR by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human SRC by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human FGFR3 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human FGFR2 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human FGFR4 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair